Practice Nurses Role in Treating Chlamydia

Practice Nurses Role in Treating ChlamydiaThe intrust nannys part in treating chlamydia and improving the versed wellness of the nationIntroductionChlamydia word has been the focus of long research interest in the ago few years. A commodious proportion of what used to be called NSU, or was even undiagnosed non- specific pathology, is forthwith recognised as macrocosm due to the chlamydia pathogen. It has now achieved the unenviable experi manpowertal condition of being considered responsible (numerically) for the greatest amount of internally transmit complaint in the UK to solar day (Dun mass 1998)Given the accompaniment that it is now t herefore recognised as being a reputation contributing horizontal surfaceor in the oerall picture of sexual health, we must catch ways in which the NHS is set up to accept the problem. (HPA 2003)As with m all an an some otherwise(prenominal)(prenominal) health think exposes such as this there atomic number 18 a number of ancillary issues that must be considered in relation to the main theme. These include the government agency of the separateing surgical process in trying to contain the preponderance of chlamydial transmission system, the practice c are fors intent in that top process, the flowing thoughts on the handling of chlamydia and the practice retains role in non only the treatment, but also the partner canvas application that is vital to try to stop the spread of the ailment. (Fenton et al 2001)The practice nurse is generally ideally placed within the simple healthc ar team to act as a central liaison purport for m twain of these activitiesIf we start by considering the whole issue of cover song. On sensation level, one could be forgiven for thinking that the issues relating to showing are actually quite simple. We spang that many cases of chlamydia are actually well (see on). Given the fact that it clear cause grand damold climb on and is eminently treatable, why non screen for it and get rid of it? Sadly, it is not as simple as that. (Simms et al 1996)The defer Institute for Clinical Excellence (NICE) has set up the National Chlamydia cover charge Programme (NCSP). It quotes its proportionalitynale for doing so asGenital Chlamydia trachomatis is the ordinaryest sexually genic tarnishion (STI) in EnglandGenital chlamydial infection is an alpha reproductive health problem 10-30% of infected women develop pelvic instigative disease (PID).A significant proportion of cases, contingently amongst women, are asymptomatic and so, are liable to remain undetected, trustting women at risk of evolution PID. application for genital chlamydia infection may reduce PID and ectopic pregnancy.The analyse itself was exemplary in design with an entry age bracket of roughly 8,000 patients. The authors considered the efficiency of several antithetical manners of check and then compared the results of the programmes against the bes of allowin g the disease to continue untreated in the community and these include all the sequelae of infertility, pelvic subversive disease and ectopic pregnancy in women together with the complications that can occur in the male partners (infertility again) and prostatitis. (Berry et al 1995)The cover even cover the incidence of both pneumonia and eye infections in their children. The structure of the content was sooner comprehensive insofar as it compared the results of four separate collectionsOne conclave received no cover at all, a second crowd were screened if they exhibited mucopurulent cervicitis, the third group included all women who were less(prenominal) than 30 yrs. old and the last group was all women irrespective of symptoms.The actual screening tool was the Polymerase chain reply (PCR) which is a in truth specific and subtile antibody based test. It was performed on either urine or direct cervical samples. (Barlow et al 2001)The study protocol then called for all po sitive examination patients to receive treatment with doxycycline for seven days.The outline section of the opus is both long and complex. We shall therefore condense our examination of this part of the study into an examination of the results.The overall treatment apostrophizes of treating all of the medical complications of chlamydial infection was calculated as $676,000.Each of the positive screening strategies produced a significant reduction in the expected cost of complications that was greater than the cost of the actual screening exercise. A condensation of the tabulated results is proven hereScreening methodScreening costs ($) aesculapian costs ($)Total cost ($) way out of PID casesPID cases pr solutionedNo screening676,000676,000152CDC criteria55,000390,000446,0008864Women 75,000297,000372,0006785Universal screening120,000270,000391,0006191The results need fiddling explanation, as it can be clearly seen that both the costings and the number of cases prevented betoken strongly for a case for screening. The only point of contention is the ratiocination on the population that the health armorial bearing system ordain fund for screening.Overall, the authors state that their regime reduced the incidence and prevalence of pelvic inflammatory disease by 60% when compared to the unscreened group.The other significant factor was that, taking all groups as an average, they mention a total healthcare parsimoniousness of approximately $50 per woman screened, and this clearly does not take any account of any associated comorbidity, pain and incuring that is caused by the chlamydia infectionA further corollary can be drawn from the results. The authors went on to provide an moving statistical analysis of the comparative costs of take issueent community groups with unalike rates of prevalence. Of great importance to our regards here was the fact that the authors concluded that the cost of screening was cost trenchant when the incidence of inf ection in a population of asymptomatic women was above 1.1%. when the incidence rose above 11% then they make up that the screening of all women and their partners became the most effective strategy. To nigh conclusion, this study can be considered the gold standard for most of the studies in this area. It is well conceived, meticulously executed and well and thoughtfully analysed to give meaty results which are of great practical importance.Despite such ac companionships it should be commemorated that there are a number of negative points to be considered in this particular study. The universal treatment constant was the seven day doxocycline treatment. We should note (as the authors did) that there is therefore a potential for non-compliance with the whole seven day regime, and this may introduce a potential source of bias in the figures(Haddix et al.1995). We can also point to other studies that pay off addressed this particular problem with a one dose treatment regime (az ithromycin). It is sportsmanlike to note that despite the potential for bias, extrapolation to these other studies does not appear to show significant differences in the overall results (Lea et al 1997)The issue of screening, although covered reasonably comprehensively in the last subject, certainly as far as matters of cost are concerned, is examined further in the written report by (Duncan et al. 2001). This paper approaches the issues from a varied perspective. It includes the issues of male screeningAnd takes an over aspect of the unexclusive wellness issues from a sociological viewpoint, which compels it, (in our examination of the current literature), almost unique.We should note that we drop already addressed the issues faced by the NCSP, but the other major humankind document in this area is the report commissioned by the heading Medical Officer (CMO 1998). It is instructional to discuss the recommendations of this group as they differ significantly from the screen ing criteria used in the previous paper. The recommended groups for screening here are the followingEveryone with symptoms of chlamydia infection,All those attending genitourinary medicine clinics,Women pursuit termination of pregnancy.1Opportunistic screening of young sexually active women beneath 25 yearsWomen over 25 with a new sexual partner or two or to a greater limit than sexual partners in the past year.In the context of our considerations here, we should note that the advisory group place the optimum sites for screening as the aboriginal healthcare team (family planning clinic) as well as the usual chewing gum clinics. (Stokes 1997)The Duncan paper is especially well written and a major point that comes from it is in snappy contrast to that found in the Howell study. One of the criteria that they suggest for screening males in the population is that women may feel that being screened has connotations of being dirty and plain A positive result is said to be associ ated with promiscuousness. The authors suggest that not screening men not only fosters gender inequalities but it reduces the Public Health cushion on the Mans responsibilities for sexual health. (Pierpoint et al 2000)There is no argument that this is a valid point, but the paper does not produce any indorse to show that male screening has a positive tinct on the cost-effectiveness of the screening procedure. (Stephenson et al 2000)The paper does however, contrast these statements with the accepted fact that women are actually easier to place than men, as they are generally heavier health care users than men in the major at risk age range. (Oakeshott et al 1998)The paper points to the need to tackle the issues of sexual inequality, as it could be considered that the screening programmes may have less than the desired effect if they are perceived by women to be niggling more than surveillance of their particular sexual habits.It draws a clear proportion between a women only sc reening programme for chlamydia and the well set up women only cervical cytology screening clinics. The paper quotes (Holgate et al 1998) in the commentThe potentially adverse consequences of sexual intercourse a private event can be surveyed and treated through screening services a publicly based and funded system . It is women who transcend this private, public dichotomy and realize their lives scrutinised in a manner alien to men . The focus is usually upon women both as transmitters and contractors of relevant viruses as both those whose cervixes are surveyed and whose sexual activity comes under(a) surveillance.The paper then has a long midst section which, as a critical analysis, is little more than a diatribe against women being singled out for screening. It is fair to say that all of the arguments put forward are valid, to a degree, but are presented with a strongly feminist viewpoint, which is both understandable and worthy of merit form a sociological standpoint. The arguments are not however, convincing from a scientific, financial or practical perspective.The conclusions of the paper are entirely justified in occupation for a greater understanding of the womans point of view when organising and running screening clinics, in order to broaden their appeal to the organize groups. (Santer et al 2000)With specific reference to the role of the nurse in the primary healthcare team screening for chlamydia we can now turn and examine an excellent paper by Grun (et al 1997) which looked at two divergent methods of screening for chlamydia in a nurse run primary healthcare setting.The study set out to try to accurately determine the prevalence of chlamydia in the North London area using the ligase chain reaction (LCR) technique which is similar to the PCR mentioned originally. (Butt et al 2001)This particular study used the rather labour intensive cervical scrape method for sampling, which had the added benefit that cervical cytology could be assess ed at the same era. The paper is quite detailed in its description of its method and appears to be rigorous in its execution. It is worthy of our consideration here because of its direct relevance to our prime consideration. The results and conclusions of the paper make for interesting readingOne of the more significant conclusions was that, on the keister of their findings, if there was a policy of simply screening all women senile 25 and all women who had had two or more partners in the past year, they would have detected 20 out of a possible 23 positive chlamydia infections in their cohort. The authors make a salient comment that including other screening criteria such as marital status (which has been suggested by other authors Lossick JG, et al 1996), would have do no statistically significant impact on their detection rate.They also make the comment, in line with the other authors we have examined, that selective screening appears to be more cost effective than universal screening, although the actual cost implications were not specifically considered in this paper. In contrast to the Howell paper, it suggests that screening become a viable tool when the community prevalence rate approaches 5%The fourth paper to be freshen uped is the more recent paper by Adams (et al 2004). This paper takes a more general overview of the whole issue of chlamydia in the UK. This is effectively a meta analysis of nineteen different papers (selected from 357 studies) which report the incidence of chlamydia as tried and true by the PCT method on urine samples. This is significant as it is the send-off meta analysis to be carried out on UK data. (Armitage et al 2001)The results are extremely detailed and many are only of marginal relevance to our considerations here. We shall restrict our comments to those aspects that are specifically relevant. Firstly, the authors comment on the current prevalence of 8.1% of the population examen positive in the under 20 age grou p, progressively diminishing to 1.4% in the over 30 group. The significance of this is that it is very much frown than other studies. For example studies set in GUM clinics put the prevalence in the under 20 age group in the region of 17% and antenatal clinics at about 12%. (Piementa et al 2003)This may therefore have relevance in targeting of specific at risk groups. It should be noted that this study gave no data with regard to the incidence of chlamydia in the male population. (Dixon et al 2002)Our comments made earlier about the asymptomatic nature of the bulk of the infections, is borne out in the fact that only 8% of those tested and found to be positive, actually volunteered that they had any genital symptoms (of any sort).Another important consequence of this study is the fact that it highlights the comparatively high detection rate to be found in attenders at primary healthcare team premises. This shows a gap in the reasoning and recommendations of the National versed Hea lth and human immunodeficiency virus Strategy for England (D of H 2002) which currently suggests targeting GUM clinics and family planning centres as prime sites for screening centres. by-line on from the reasoning expounded in the last paper, we can look at a provocatively entitled article by Kufeji (et al 2003) Who is being tested for genital chlamydia in primary care?The paper makes the point that we already have enough evidence to clearly identify the target populations that are the most likely to give a good go as far as screening is concerned (viz. the most at risk groups). The raison dtre of this paper was to compare the characteristics of the actual groups screened with the characteristics which we know to be recreateative of the groups most likely to be at risk. The corollary of this reasoning being that if the two groups do not match then all the calculations made about the cost effectiveness of a selective screening process do not hold water. (Kinn et al 2000)The most s triking suffer of this paper is the fact that we know (Adams et al 2004) that the maximum age incidence for chlamydia is in the sexually active under 20 age group and the incidence rapidly decreases with age to the over 30 age group. Kufeji and his co-workers found that the absolute majority of the tests do (63%) were done on the over 25 yr. age group where we would expect the results to be positive only in about 1.5% of the population. Adams findings were confirmed with a positive rate of 13.3% found in the under 20 yr. olds tested.The paper also point to the fact that the practices studied had a comparatively high healthcare staff to patient ratio. In the practices where the ratio was lower, even less opportunistic testing was done. (Shefras et al 2002)This correlates to the finding that the Townsend stigmatize ( of social deprivation) correlated highly with both a reduction in the amount of testing and an increase in the prevalence of chlamydia. In the nomenclature of the a uthors the study points to the fact that screening programmes for chlamydia in primary healthcare settings suffer from a selection bias and social desirability bias, and they do not aim to provide complete descriptive information on testing patterns a miscegenation a population.It should be noted that this particular study was not just on a small sample. The authors took as their entry cohort all of the 119 General Practices in Nottingham which collected a total of over 7,000 samples. The authors note that the number of tests done in General Practice is change magnitude at about 35% per year. It follows that if a significant number of these are inappropriately targeted, this has profound implications for the related costings of the exercise.One other salient point in this study was the fact that only 1 in 40 tests were done on men. (Chernesky et al 1999)The last major paper that we shall review in this section is the paper by Cassell (et al 2003) this deals with the thorny issue of partner notification when screening turns up a positive result. besides connection tracing had largely been in the realms of the GUM contact tracing nurse. With the expansion of the screening role into the realms of General Practice and other clinics, the contact tracing role has also expanded and may well have lost some of its efficiency due to both a lack of skill, time and resources. (D of H 2002).Cassell and her colleagues have tried to investigate the extent to which this perceived reduction in contact tracing may be responsible for the relentless increase in the overall incidence of chlamydia. (Radia et al 2001).The study was done by postal questionnaire to all GPs in Nottinghamshire. They got a 56% response rate. Arguably the most significant finding of the study was the fact that 86% of respondents considered that chlamydia testing was part of the remit of the primary healthcare team, while only 40% considered that partner notification was a primary healthcare team role. The rationale for this was, that most of the non-contact tracing respondents felt that it was their role to inform the patient that they should inform their partners.Given the fact that we have evidence from the Duncan paper that women tend to equate a positive test with promiscuity and being dirty, it is perhaps not surprising that a straightforward number of partners do not get told. If you add to this number the enigmatical number of chlamydia infections that may have come from clandestine or adulterous liaisons, then this number may be higher still. This is clearly both hypothesis and conjecture but it would seem to be dictated by common finger.The paper goes into considerable detail about the reasons why different primary healthcare teams have different practices, but rather worryingly a surprising 20% treat chlamydia with a dose of antibiotic which is less than the currently recommended therapeutic level recommended by the Central size up radical for Genitourinary Medicin e, (Stokes et al 1997)The problem of a postal questionnaire study is that there is an intrinsic bias in the study design. It is quite thinkable that the 56% of primary healthcare teams who responded were the ones who may have been sufficiently make to be positive about matters to do with chlamydia and may therefore have been better informed that those who did not respond. In the words of the authors our study probably over-represents primary healthcare teams already testing for chlamydia and may exaggerate the extent of good practice.The paradox outlined by this study is that while the majority of GPs and their teams are already willing to assume the mantle of diagnosing and managing chlamydial infection, the same majority agree that contact tracing is the main difficulty in managing these patients. The study made enquiries relating to the presence of follow up strategies which were designed to minimise the risk of further infection and found that there was very little evidence to be found other than by set the onus on the patient to tell their partners.It follows from this observation, and the authors put it quite compactlyIf testing in primary care continues to increase without adequate co-occurrence for partner notification, much of the resource used in testing women will be wasted. (Griffiths et al 2002)If we accept the premise that an increasing amount of chlamydia screening will be done in General Practice in the future, it is likely that an increasing proportion will fall to the practice nurse or the family planning nurse specialist. (Stokes et al 2000). If this is the case, then it is common sense to maximise the benefit of chlamydia screening by supporting the healthcare professionals with time and resources to perform proper contact tracing to minimise the risk of re-infection. (EHC 1999)ConclusionsIn this review we have selected six primary papers which each represent a significant contribution to the evidence base in our knowledge of the rat ionale for screening and treatment of chlamydia infection. (Sackett 1996)From our examinations it is clear that there is a considerable disparity in the figures pertaining to the prevalence of chlamydia infection in the community. The paper by Adams (Adams et al 2004) gives us a partial rationale for this and that is that studies done in different areas of health care practice will yield different results because they have a different clientele. It is not, perhaps, surprising that a study done in a GUM clinic will report different prevalences than a study done in a General Practice setting.The common factor that runs through all of the papers examined is the fact that it is rare to find that men are screened. Generally the figures suggest about 2-5% of men are screened when compared to the number of women. There is no evidence to suggest that they have lower infection rates than women and, according to Duncan (et al 2001), there are a number of very good sociological reasons why men should be screened as frequently as women.The fact of the matter is that women are subject to screening with much greater frequency than men and therefore give birth the brunt of both the indignity and the responsibility.There is no doubt however, that the case for screening and treatment and contact tracing is made on both economic and health grounds. It is equally clear that the practice nurse has a central role in the efficient administration of all of these vectors to varying degrees. The advent of nurse prescribing (Legge 1997) will make the practice nurse as valuable in this area as they already are in both the screening and contact tracing roles. 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